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Unexplained weight loss is the term used to describe a decrease in body weight that occurs unintentionally and can be a warning sign of diabetes. They can signpost you to local weight loss and exercise groups and talk to you about losing weight and exercising safely. Learn How Many Calories You Burn Every Day. Insulin makes people overweight by acting on the brain to cause hunger, making the liver manufacture fat and fill fat cells in the stomach. 15% Weight Loss Calculator (Kgs) Body Mass Index (BMI) and Waist Size. Information and advice for adults and children about healthy weight, including how to find out if you’re a healthy weight. Or, those with a bmi range of over 35 with related health conditions (heart disease, diabetes type 2, sleep apnea and high blood pressure). Losing or gaining too much weight can cause periods to stop. 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